Editorial: pressure to close the therapeutic window of non-selective beta blockers?

Nonselective Beta-blockers in Patients with Cirrhosis: "the Therapeutic Window".

For over 30 years, nonselective beta-blockers (NSBB) have been successfully used for preventing variceal bleeding in patients with cirrhosis and portal hypertension. Nevertheless, recent studies suggest that NSBB may be effective only within a particular "therapeutic window" in patients with advanced liver disease. Outside of this window, in early stages of cirrhosis and in very advanced cirrho...

Editorial: Beta-blockers and the eye.

consequence analysis of the leakage, ignition and explosion during high pressure sour gas injection process to the oil reservoir

there is no doubt that human being needs to become integrated with industry and industry needs to be progressed, daily. on the other hand, serious events in industrial units specially in oil industries has been shown that such damages and events are industry related ones. the consequence of such events and damages which resulted in chemical and poisoned explosions and loss of life and property ...

Can hypersplenism secondary to portal hypertension be treated by non-selective beta blockers?

Hypersplenism in chronic liver diseases (CLD) is characterized by splenomegaly and thrombocytopenia. Thrombocytopenia is a contraindication to percutaneous liver biopsy, which is an important procedure for diagnostic work-up of liver disease. In children, the etiologies of CLD are more diverse than in adults, and include congenital, metabolic and infiltrative diseases as well as viral hepatitis...

Is the use of non-selective beta-blockers necessary in cirrhotic patients with small varices?

Non-selective β-blockers (NSBBs) could eff ectively prevent the development of fi rst variceal bleeding in cirrhotic patients with medium/large varices. However, as recently reviewed by Giannelli et al [1], the clinical benefi t of NSBBs remains controversial in cirrhotic patients with small varices. In line with their considerations, we would like to further comment on the controversy. A previ...